Abstract

Women undergo a physiological process called pregnancy, which comes with some health complications for both the mother and the unborn child. [1] Hypertension is one significant problem affecting 7% - 10% of pregnancies and causes maternal and neonatal death and morbidity. [1] Approximately 5% – 7% of pregnancies are affected with PIH, while the incidence ranges from 5% to 15% in India.2 Objectives: To study and compare the haematological parameters in PIH patients to normotensive pregnant women. Material & Methods: Study Design: Hospital based observational study. Study area: Department of Physiology and Obstetrics and Gynaecology, Government medical college. Kadapa, Andhra Pradesh. Study Period: 1 year. Study population: Pregnancy induced hypertensive pregnant women and normotensive pregnant women visiting the Obstetrics and Gynaecology department. Study tools and Data collection procedure: Cases comprised of Primi-gravida at 3 rd trimester, with known cases of Pregnancy Induced Hypertension admitted in hospital for safe institutional delivery. The control group are the women primi-gravida who have attended the regular O.P. and I.P. Five ml of blood anti -coagulated with EDTA was collected and various haematological parameters were studied. These included Hemoglobin, total and differential counts, Platelet count, red cell indices like PCV, MCV, MCH, MCHC and BT, CT, Prothrombin and APTT. Results: The mean for platelet count in control group was 2.21 and study group was 1.67. The estimated P value for platelet count in control group and study group was <0.001. The mean for APTT in control group was 25.33 and study group was 27.2. The estimated P value for APTT in control group and study group was <0.001. Thus there was significant decrease in platelet count in study group compared to control group. Conclusion: Using the absolute platelet count as a gauge, we can evaluate pregnancy-induced hypertension. Therefore, it is important to detect the illness early, stop it from becoming worse and developing into eclampsia, and lower foetal morbidity and mortality.

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