ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Comparison of hemodynamic and respiratory effects of dexmedetomidine combined with propofol versus fentanyl propofol with propofol being control for insertion of laryngeal mask airway


    Dr. Akula Maheswar Rao, Dr. Vaddi Preethi, Dr. Kandukuri Sneha, Dr. Gade Bharathi
    JCDR. 2023: 3463-3470

    Abstract

    Comparison of Hemodynamic and Respiratory Effects of Dexmedetomidine Combined with Propofol Versus Fentanyl Propofol with Propofol as Control for Insertion of Laryngeal Mask Airway. To evaluate and compare hemodynamic parameters including heart rate (HR), mean arterial pressure (MAP) and oxygen saturation (spo2), in Dexmedotimidine propofol group, Fentanyl Popofol group and only propofol group. To evaluate and compare respiratoy parameters mainly Respiratory Rate (RR) in Dexmedotimidine propofol group, Fentanyl Popofol group and only propofol group. Methods: This was a prospective randomized study that was conducted in the Department of Anaesthesia, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India, during the period of June 2022 to November 2022. The study was approved by the hospital ethics committee. Results: The Mean Age of patients who had Dexmedetomidine and Propofol is 30±7 Years, Fentanyl and Propofol is 31±7 Years, and Propofol alone is 30±6 Years, which is not statistically significant. Fentanyl plus Propofol patients weigh 53±8 Kgs, whereas those who received just Propofol weigh 52±7 Kgs. This difference is insignificant. Dexmedetomidine and Propofol pre-operatively had a greater mean arterial pressure during LMA insertion, but after 1 min, 3 min, 5 min, and 10 min, their mean arterial pressure was lower than Fentanyl and Propofol. This difference was statistically significant throughout. Conclusion: In contrast to group F, which used fentanyl and propofol, and group P, which used propofol alone, our study demonstrated that the effects on hemodynamic and respiratory parameters are more stable in Group D, which used dexmedetomidine with propofol. When used separately for co-induction with propofol to insert an LMA, dexmedetomidine and fentanyl produce excellent overall insertion conditions with haemodynamic stability. Additionally, the need for an induction dose of propofol for LMA insertion is significantly reduced by dexmedetomidine. When inserting a LMA, propofol is the ideal induction agent. Haemodynamic instability may result when used alone.

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    Volume & Issue

    Volume 14 Issue 1

    Keywords