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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    COMPARISON OF INJECTION LIGNOCAINE (PRESERVATIVE FREE) 1.5 MG/KG IV WITH ORAL PREGABALIN 150 MG FOR ATTENUATION OF HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND INTUBATION


    Dr. Wankhade Prachi Pandit, Dr. Jitendra Deodas Bhalerao, Dr. Naik Jagdish Jaipalrao, Dr. Mansi Pravin Sawarkar
    JCDR. 2024: 1467-1474

    Abstract

    Background Laryngoscopy and endotracheal intubation are associated with a transient hemodynamic stress response which needs attenuation. The anesthesiologists have tried various methods and drugs for this purpose. The aim of present study was to investigate the effects and comparison of intravenous lignocaine 1.5mg/kg and oral pregabalin 150mg on blunting haemodynamic stress response. Method Total 80 adult patients of ASA grade I and II were enrolled in this study and randomly allocated into two groups of 40 each. Group I (n=40): Patients received injection Lignocaine (preservative free) 1.5 mg/kg iv 3 minutes prior to laryngoscopy. Group II (n=40): Patients received oral pregabalin 150 mg 1 hour prior to laryngoscopy. HR, SBP, DBP and MAP were recorded before induction considered as 0 minute and 1, 3, 5 and 10 minutes after laryngoscopy and intubation.

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    Volume 15 Issue 1

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