Abstract

Lower limb surgeries may be performed under local, regional (spinal or epidural) or general anesthesia, but neuraxial blockade is the preferred mode of anesthesia. The present study was conducted to compare intrathecal dexmedetomidine and magnesium sulfate as adjuvants to bupivacaine in total hip replacement. Materials & Methods: 60 ASA physical status I and II patients aged 18–45 years, of either genderscheduled for total hip replacementsurgery under spinal anesthesiaof both genderswere divided into 3 groups of 20 each. Group I received 15 mg hyperbaric bupivacaine and 0.1 ml (10 μg) DXM, group II received 15 mg hyperbaric bupivacaine and 0.1 ml (50 mg) Mg and group III received 15 mg hyperbaric bupivacaine and 0.1 ml normal saline as control. Parameters such as onset times of sensory blocks, motor blocks, regression times of sensory blocks and motor blocks were compared. Results: The mean height in group I was 157.4 cm, in group II was 160.2 cm and in group III was 158.4 cm. The mean weight was 64.2 kgs in group I, 63.8 kgs in group II and in group III was 61.5 kgs. The mean BMI was 22.3 Kg/m2 in group I, 24.0 Kg/m2 in group II and in group III was 23.1 Kg/m2. The difference was nonsignificant (P> 0.05). The mean onset of sensory block (hour) was 2.3, 6.1 and 4.8, onset of motor block (hour) was 3.4, 7.2 and 4.9, regression time of sensory block (mins) was 312.4, 248.4 and 198.6 and regression time of motor block (mins) was 340.6, 232.6 and 184.8 in group I, II and III respectively. The difference was significant (P< 0.05). Conclusion: Intrathecal DXM supplementation of spinal block is a good alternative to intrathecal Mg as it produces earlier onset and prolonged duration of sensory and motor block

Description

.