Abstract

Post operative sore throat is a very dreadful and 2nd most common complications in patients undergoing tracheal intubations and is developing as major reason of patient’ s dissatisfaction.. Incidence of 21-68% has been reported in studies. We compared Magnesium sulphate gargle and nebulization in preventing POST. Materials and Method: After obtaining written informed consent and permission from institutional ethical committee, 70 patients scheduled for surgery under GA were enrolled and equally divided randomly by chit and box method in two groups: Group A: nebulized with 3ml of isotonic Magnesium sulfate for 15 minutes at 5mins before induction of anaesthesia. Group B: Patients were given Magnesium sulfate gargle (20mg/kg in 30ml of 25 % Dextrose water) at 15 minutes before induction of anaesthesia. Haemodynamic parameters –H.R, SBP, DBP, R.R and SpO2 was measured intraoperatively. After extubation, severity of POST was assessed at 0hr, 2hrs, 4 hrs, 6hrs, 12 hrs, 24hrs and 48 hrs by VAS scale and grading of POST was done by 4 point scale (0-3) and compared between the groups. Results: On comparing the groups, no significant statistical difference was found between haemodynamic parameters. The mean score of POST was significantly more in group N at 2,4,6 and 12 hours (p value0.001,0.01,0.002 and 0.001).VAS score was observed significantly more in group N patients in compare to group G at 0,2,4,6 and 12 hours after extubation (p value-0.018,0.007,0.012,0.001 and 0.022).No significant complications were found.

Description

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