Abstract

Background: Objective: This study aims to compare the effectiveness and safety of ketamine, tramadol, and dexmedetomidine in the prophylactic treatment of shivering after spinal anesthesia. Methods: A randomized controlled trial was conducted involving 200 patients undergoing surgeries requiring spinal anesthesia. The participants were equally divided into three groups to receive either ketamine, tramadol, or dexmedetomidine as a prophylactic measure against shivering. The primary outcome measured was the incidence of shivering, while secondary outcomes included monitoring hemodynamic parameters and noting any adverse effects. Results: The incidence of shivering was significantly lower in the dexmedetomidine group compared to the ketamine and tramadol groups. Hemodynamic parameters remained stable across all groups, with minimal and manageable side effects. Tramadol and ketamine were effective to a lesser extent but were associated with more side effects compared to dexmedetomidine. Conclusion: Dexmedetomidine demonstrates a higher efficacy and better safety profile in preventing shivering after spinal anesthesia compared to ketamine and tramadol. These findings suggest that dexmedetomidine can be considered a preferred choice for preventing shivering in patients undergoing surgeries with spinal anesthesia. Further studies are recommended to confirm these findings and explore long-term outcomes.

Description