Journal of Cardiovascular Disease Research
Comparison of thyroid hormone profile among fertile and infertile females
Dr. Bharat Bhushan Tayal, Dr. Nishant Tayal, Dr. Komal Tayal, Dr. Uma, Dr. Sudhanshu Agarwal
JCDR. 2023: 1587-1591
Abstract
To compare the thyroid hormone profile (T3, T4, TSH, Anti-TPOAb, & TBG) in females who are able to conceive and those who are not. Material & Methods: The sample consisted of 88 individuals who were divided into two groups. group A (infertile) and group b (control) (group B). We used non-probability purposive sampling because each group's subjects were selected in accordance with predetermined criteria. All subjects who matched the qualifying requirements were registered for the current inquiry. Each participant provided written consent before participating. Information was received under tight confidentiality. Utilizing IBM SPSS version 23, data was examined. Results: Between the two study groups, there were substantial differences in serum T3, T4, TSH, anti-TPOAb, and TBG levels. TSH and anti-TPO antibodies showed a significant mean difference between the fertile and infertile samples, with a p-value less than 0.05. Conclusion: All of the participants in this study had T3, T4, TSH, and TBG levels that were within the typical pre-pregnancy reference range. When UE infertile females' thyroid hormone profiles were compared to those of fertile females, a tendency towards subclinical hypothyroidism and the occurrence of anti-thyroid antibodies were found.
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