Abstract

Pulmonary dysfunction is a frequent postoperative complication in patients undergoing coronary artery bypass graft (CABG) surgery and atelectasis is thought to be one of the main causes. Development of atelectasis is associated with decreased lung compliance and impairment of oxygenation. Post-CPB-induced lung atelectasis accounts for most of the marked post-CPB increase in intrapulmonary shunt and hypoxemia. Mechanical ventilation can be harmful to these atelactic lungs, especially when high tidal volumes and pressures that cause lung over distension are used. Pressure-controlled ventilation (PCV) needs frequent titration of the inspiratory pressure to deliver a set tidal volume, whereas pressure-regulated volume-controlled (PRVC) ventilation mode provide the target tidal volume with the lowest possible airway pressure

Description