Journal of Cardiovascular Disease Research
Concurrent quantitative analysis of Abacavir Sulfate and Lamivudine in Combined Dosage Form using First Derivative Zero-Crossing and Ratio First Derivative Spectrophotometric Techniques
DIPTI B RUIKAR , DITI J DESAI , BANSARI MYANGAR , SADHANA J RAJPUT ,GAJANAN J DESHMUKH
JCDR. 2017: 387-394
Abstract
Two simple, sensitive, specific and accurate spectrophotometric methods are proposed in the present work for the simultaneous estimation of Abacavir sulfate (ABA) and Lamivudine (LMV) in their binary mixture. In first derivative zero crossing technique the absorbances at 234.2 nm (zero crossing point of LMV) were plotted against the respective concentrations of ABA.
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