ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    CORRELATING FACTORS FOR ACHIEVING TARGET SERUM URIC ACID LEVELS AND INCIDENCE OF GOUTY ARTHRITIS: A RETROSPECTIVE OBSERVATIONAL STUDY


    Dr.Priyanka Vaitla , Dr.Akula Satya Preethi , Dr. Sailusha Sreerama , Dr.Sandhya Sadula
    JCDR. 2023: 294-300

    Abstract

    Gouty arthritis is a common and debilitating form of inflammatory arthritis caused by the deposition of uric acid crystals in the joints Objectives: To identify the correlating factors associated with achieving target serum uric acid (SUA) levels and the incidence of gouty arthritis.Methods: A cohort of 500 patients diagnosed with gouty arthritis who underwent regular monitoring of SUA levels was included in the study. Demographic data, medical history, lifestyle factors, comorbidities, and medication use were collected. The primary outcome was the achievement of target SUA levels, defined as maintaining SUA levels below 6.0 mg/dL. The secondary outcome was the incidence of gouty arthritis episodes during the study period..Results: The mean age of the patients was 52.7 years, with 72% being male. Among the cohort, 58% of patients achieved target SUA levels during the study period. Logistic regression analysis revealed several significant factors associated with achieving target SUA levels. Medication adherence was found to be strongly associated with achieving target SUA levels (odds ratio [OR]: 2.15, 95% confidence interval [CI]: 1.67-2.76). Additionally, patients who made dietary modifications had higher odds of achieving target SUA levels (OR: 1.82, 95% CI: 1.34-2.48). Comorbidities such as hypertension were also significantly associated with achieving target SUA levels (OR: 1.57, 95% CI: 1.18-2.08).Regarding the incidence of gouty arthritis episodes, logistic regression analysis identified two significant factors. Patients with SUA levels above 7.0 mg/dL had higher odds of experiencing gouty arthritis episodes (OR: 2.43, 95% CI: 1.87-3.15). Furthermore, obesity was found to be a significant risk factor for gouty arthritis (OR: 1.89, 95% CI: 1.42-2.51).Conclusion:Medication adherence, dietary modifications, and comorbidities such as hypertension were associated with achieving target SUA levels. High SUA levels and obesity were significant risk factors for the incidence of gouty arthritis episodes

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    Volume & Issue

    Volume 14 Issue 6

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