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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Correlation of antioxidants and IgE levels and its comparison with ADAM33 gene polymorphism (V4) in asthma patients of Jammu and Kashmir


    Kiran Gupta, Dr Arun Mishra, Dr Ashraf Ali Khan, Sumit Deb Nath
    JCDR. 2023: 1100-1104

    Abstract

    Asthma is a severe breathing disorder which effects the bronchial airways and makes it difficult to breath out. Many factors like increase in biochemical markers, environmental factors and genetic polymorphism can be associated with the onset of Asthma. The aim of this study is to determine whether IgE and antioxidant levels are associated with genetic polymorphisms of the ADAM33 gene (V4) in both healthy and asthmatic patients. Materials and methods: The study was conducted in 100 patients (70 asthmatic and 30 normal) at GK labs Srinagar J&K India. Results: In this study, we found that there is a significant correlation between IgE and antioxidant levels in asthma patients compared to controls in population of Jammu and Kashmir where there was an increase in IgE level and decrease in antioxidant level in addition to ADAM33(V4) gene polymorphism.

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    Volume 14 Issue 2

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