Abstract

Researchers have documented instances of direct cardiac involvement in individuals with dengue fever, indicating a possible link between heart malfunction and the onset of shock. The objective of this study was to establish a correlation between cardiac symptoms and the severity of dengue fever. Material and Methods: The study comprised a cohort of 200 individuals who had symptoms consistent with dengue fever. The presence of Dengue NS1 antigen was identified using the Enzyme Linked Immunosorbent Assay (ELISA) technique. Every patient had Electrocardiography (ECG) for all leads in addition to 2-dimensional Echocardiography (ECHO). The samples were labeled and tested for indicators of acute cardiac myocyte injury, such as total CK, CK-MB, and Trop T, by an investigator who was uninformed of the clinical state of the participants. Results: The study comprised patients aged between 20 and 60 years, with a mean age of 39.23 ± 90.9. Among the many cardiac signs found in the patients, bradycardia was the most prevalent, occurring in the majority (40%) of the patients. Among the 96 patients who had abnormal CK-MB levels at admission, 82 individuals were seen to have normal CK-MB levels upon discharge. Upon admission, troponin I tested positive in 26 individuals. Upon arrival, 124 individuals exhibited a normal electrocardiogram (ECG), whereas 96 patients displayed ECG changes. Conclusion: ECG, cardiac enzymes, and echocardiography are the primary diagnostic methods for identifying myocardial involvement in cases of dengue fever. The degree of cardiac involvement was greater in DHF and DSS cases compared to DF cases

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