Abstract

Introduction: Perinatal asphyxia is an important cause of admission to neonatal intensive care units (NICU) with multi organ dysfunction.Aim: Determine the change in functional echocardiographic parameters with CKMB and Troponin I and time. Methodology:The study, conducted at the Division of Pediatric Cardiology in M.D.M Hospital under the Department of Paediatrics, Dr. S. N. Medical College, Jodhpur, focused on perinatal asphyxia and hypoxic ischemic encephalopathy (HIE).Functional echocardiographic parameters were studied with time. Result: Both left atrial and aortic diameters did not significantly change over time. However, La/Ao showed a significant decrease over time. LVED and LVES remained relatively stable over the measured time intervals. EF and FS increased significantly over time, indicating improvement in cardiac function. Parameters such as LVMPI, mvcf, MAPSE, and TAPSE did not show significant changes over time. Mitral E/A ratio, mitral E/e' medial, mitral E/e' lateral, tricuspid E/A ratio, tricuspid E/e' medial, and tricuspid E/e' lateral also remained relatively stable over the measured time intervals. Conclusion: It shows a complex interplay between structural and functional aspects of cardiac performance over time. While certain parameters remained stable, others demonstrated dynamic changes, underscoring the importance of comprehensive echocardiographic assessment in evaluating cardiac function and guiding clinical management.

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