Abstract

Gallstone formation results from many complex factors working together. The pathologic factor related to gallstone formation is still the hot debate. In the present study we aim to correlate various gallstone characteristics (number, size, and morphological types,) with clinical indices of cases (Haemoglobin, TLC, DLC, Blood sugar, SGOT, SGPT, Alkaline phosphatase, total serum bilirubin, direct serum bilirubin, Indirect serum bilirubin, total serum protein and albumin values) and also with diabetes mellitus, smoking, tobacco chewing, alcohol intake and dietary habits. Material and methods: The patients who attended surgical outdoor, casualty department and admitted in the surgical units of GMC Amritsar, whose clinical and radiological diagnosis of Cholelithiasis and eligible for cholecystectomy were considered. Total of 50 cases were observed for this study. Results: Single stones were present in 15 (30%), double in 6 (12%) and multiple in 29 (58%). In 29 (58%) type of stones was cholesterol, in 9 (18%) pigmented and in 12 (24%) was mixed. Shape of stone was round in 19 (38%), irregular in 15 (30%), facet in 12 (24%) and others in 4 (8%). Out of 50 patients, diabetes mellitus was present in 6 (12%) and absent in 44 (88%). There was no correlation of HB, TLC, Neutrophils, Lymphocytes, FBS, SGOT, SGPT, bilirubin (T), bilirubin (D), TSP, S. albumin with number of stones (P> 0.05). There was no correlation of HB, TLC, Neutrophils, Lymphocytes, FBS, SGOT, SGPT, bilirubin (T), bilirubin (D), TSP, S. albumin with type of stones (P> 0.05). There was no correlation of HB, TLC, Neutrophils, Lymphocytes, FBS, SGOT, SGPT, bilirubin (T), bilirubin (D), TSP, S. albumin with shape of stones (P> 0.05). Conclusion: Cholesterol type of gallstones was more common among males and females and association of biochemical indices needs further exploration.

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