Journal of Cardiovascular Disease Research
Correlation of postprandial lipid profile with glycosylated hemoglobin (HbA1c) levels in Type 2 Diabetes Mellitus
Pranshu Gupta, Mahendra Tilkar, Dinesh Kumar Malviya, Manoj Prajapati, Palak Sharma, Sawan Kumar Shukla
JCDR. 2023: 1437-1445
Abstract
Post-prandial diabetic dyslipidemia creates proatherogenic conditions which are associated with microvascular and macrovascular complications. Its timely identification might help prevent complications. Aim: To study postprandial lipid abnormalities in Type 2 Diabetes Mellitus and its correlation with glycosylated hemoglobin levels in patients attending SGMH, Rewa, M.P. Method: This was a cross-sectional study done from April 2021 to March 2022 in SSMC & SGMH Rewa (M.P.). 200 cases were taken as per inclusion and exclusion criteria. Relevant examination and investigations including post-prandial lipid profile were done. All data were compiled and compared with previous studies. Results: The findings of the postprandial lipid profile in Type 2 diabetes mellitus and its correlation with glycosylated hemoglobin, revealed the following observation. In the postprandial state, triglyceride (TG) levels of >150 mg/dl were found in 82% of cases, very low-density lipoprotein cholesterol (VLDL-C) levels of >40 mg/dl, were found in 46% of cases, and, high-density lipoprotein cholesterol (HDL-C) levels of < 35 mg/dl, were found in 80% of cases. The study showed that cases had a statistically significant positive correlation between HbA1c and Triglyceride (r value 0.9756), VLDL (r value 0.9134), and Total Cholesterol (r value 0.3914) while a statistically significant negative correlation between HbA1c with HDL (r value -0.025)
» PDF