Abstract

Acute appendicitis is one of the most commonly abdominal emergencies in surgery. Several scoring systems developed on the basis of clinical history and physical examination and ultrasound imaging to arrive at a diagnosis but still acute appendicitis or appendicular perforation cannot be predicted by any specific markers. This study was to establish correlation between raise of serum bilirubin and severity of appendicitis and its specificity in diagnosing it. Materials & Methods: This was a prospective observational study carried out in the Department of General Surgery, Kalinga Institute of Medical Sciences. Total 90 patients were selected for the study with thorough clinical assessment, laboratory investigations, ultrasound findings. After confirming the diagnosis of Acute Appendicitis, the patients had undergone operative intervention. In all patient’s liver function, serum bilirubin along with liver enzyme assay was done and the findings were correlated with severity of appendicitis and its complications. Results: Out of total 90 patients 58 were male and 32 were female with mean age of the patients participated is 32.34 years. Mean total serum bilirubin of the patients with diagnosis of acute appendicitis is 0.61mg/dl with a standard deviation of 0.34 and those with diagnosis of Appendicular perforation is 1.41 mg/dl with a standard deviation of 0.90. Mean SGOT and SGPT have mildly raised with perforated appendicitis. Conclusion: Study conducted suggested that there is a significant raise of serum bilirubin levels in the cases of severe acute appendicitis. Along with clinical and radio imaging, study of serum bilirubin levels pre-operatively will be an effective indicator in cases of acute appendicitis in grading the severity of appendicitis

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