Abstract

Diabetes Mellitusis ametabolic disorder of multiple aetiology characterized by presence of hyper glycaemia with disturbances of carbohydrate, protein and lipid metabolism duetod efects in insulinse cretion, action or both.Increasing concentration of iron and ferritin incells could cause resistance to insulin and dysfunction of beta cells of pancreas. Early identification helps india gnosing grievous systemic manifestations and their prompt and appropriate treatment. Aim:To find association and correlation of serum ferritin with glycated haemoglobin (HbA1c) inpatientswithtype2diabetesmellitus. Methods: An observational study was carried out over a span of 1.5 years who were previously diagnosed case of type 2 Diabetes Mellitus attended Medicine department OPD and IPD between age group 35-70 years were included in study.Serum Ferritin, HbA1c,FBS,PPBS and other clinical features were noted based on history and clinical examination of thesepatients. Results:A totalof 100 patients (53 males and 47 females;meanage years) oftype 2 Diabetes Mellitus were evaluated. Majority ofthe subjects were in age group 51-60 years (n=34) with (meanage years 51.38±11.52 years). Therewasastatisticallysignificantdifferencepresentin mean FBS level, mean PPBS leveland mean HbA1c level, when compared between subjects having high and normal serum ferritin level (p=0.009, p=0.036, p<0.01, respectively). We comparedserum ferritin with fasting blood sugar,post prandial blood sugar and HbA1c levels and coefficient of correlation among study subjects were +0.40, +0.45 and +0.51 respectivelywithpvalueof <0.01.

Description

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