Abstract

Smoking is currently the most preventable cause of diseases and death worldwide and is one of the causative risk factors for developing cancer in different organs. Hence, it is necessary to detect potentially malignant lesions at their incipient stage. Oral cancers commonly affects floor of the mouth, soft palate, lateral border of the tongue and other areas of the mouth. Aim and Objective: The present study was the Cytomorphometric Changes In The Buccal Mucosal Cell In Smokers In Central Indian Populations. Material and Methods:A comparative study conducted among smokers of Central India population, was performed on 200 males under the age group of 20-60 years.The subjects were chosen randomly from IPD and OPD patients of Medicine Department of Index Medical College and Hospital, Indore. Results: There was significant difference observed between non smoking and smoking for cells with binucleation pyknosis, perinuclear halo, cytoplasmic granules, karyolsis, karyorrhexis, and micronuclei, in buccal mucosal cells but non significance difference was found for cytoplasmic vacuoles between nonsmoking and smokers. similar study of non-smoking populations.Conclusion: The present study indicates that almost all cytomorphological findings were high in smokers than non-smokers. Early detection of oral cancers becomes complex as they are mostly innocuous and asymptomatic during their initial stages, Cytomorphometric analysis can be used regularly to detect these cell alterations. Currently, use of exfoliative cytology has increased as an adjunct to screening of precancerous lesions and malignancies of the oral cavity

Description

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