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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Dermatophyte Prevalence and Antifungal Resistance in Central India: Insights from a Clinical and Mycological Study


    Vaibhav Gupta , Chinithung Ngullie , Akshaya Khattri , Harsha Gupta , Kuldeep Singh , Rajdeep Paul
    JCDR. 2024: 858-861

    Abstract

    Superficial fungal infections are among the most prevalent fungal diseases globally, especially in tropical regions like India. This study aimed to isolate, identify, and assess the antifungal susceptibility of fungal agents causing mycoses in patients at a tertiary care hospital in central India. Clinical samples from 200 patients were analyzed through KOH examination and culture isolation, with identification based on colony morphology, pigment production, and microscopic examination. Antifungal susceptibility was determined using the broth dilution method to find the minimum inhibitory concentration (MIC). Results showed that dermatophytes, particularly Trichophyton mentagrophyte, were the predominant isolates. Terbinafine exhibited the highest efficacy, with the lowest MIC value of 0.03μg/ml, while fluconazole had the highest MIC value of 32μg/ml

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    Volume 15 Issue 5

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