ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Determination of Osteocalcin, Osteopontin,Osteonectin Hormones and Interleukins levels in Postmenopausal Women Osteoarthritis in Kirkuk City


    Fidan Fikrat Ahmed
    JCDR. 2023: 3301-3308

    Abstract

    The current study included the collection of 80 samples, 50 samples from patients with osteoporosis and 30 samples from non-affected women (control group) whose ages ranged between (55-80) years. The samples were gathered from outpatient medical clinics in Kirkuk, and then blood was drawn from healthy and sick persons and separated using a centrifuge. The centrifuge was used to assess the amounts of C-reactive protein, osteocalcin, osteopontin, osteonectin, Interleukin-IL-6 and IL1.The current study found a substantial increase (P ≤0.05) in the level of hs-CRP in patients with osteoporosis, as it was (0.917 ±0.368) ng /ml, while the control group (healthy women) was (0.588 ±0.132) ng / ml, and a significant drop (P≤0.05) in the concentration of Osteocalcin.as it was (0.921±0.098) ng/ml in osteoporosis patients, while the control group (healthy women) was (1.8010.199) ng/ml, and a significant increase (P≤ 0.05) in the level of Osteopontin was (2.789 0.891) ng/ml in osteoporosis patients, while the control group (healthy women) was (0.987 ±0.296) ng/ml, And a substantial increase (P ≤0.05) in the level of Osteonectin, which was (2.8960.567) ng / ml in osteoporosis patients.While the control group (healthy women) was (1.409±0.164) ng/ml, and a substantial rise (P≤ 0.05) in interleukin-6 concentration. It was (20.53 ±26.536) ng / ml in osteoporosis patients, whereas the control group (healthy women) was (10.23±01.987) ng / ml, and there was a significant rise (P ≤0.05) in the interleukin-1β among the patients (16.044±1.252) ng / ml. Female osteoporosis patients served as the control group (healthy women), while it was (8.7871.980) ng/ml in the healthy women group.

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    Volume 14 Issue 1

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