Abstract

Early recognition of myocardial dysfunction may help in the management for quick and improved outcome. Experimental models of myocardial injury have shown significant rise in cardiac troponins (cTns) and creatine phosphokinase-MB (CPK-MB). Material and Methods- Cardiac trop T and ck-mb is recorded in 100 children with in 24 hrs of admission in picu who are critically ill excluding cardiac cases. Result- Cardiac troponin T has been used to assess prevalence of myocardial injury in critically ill children. Myocardial injury has been associated with increased mortality. The present study was observational study conducted in Paediatric Intensive care unit of tertiary care centre, Dr. Susheela Tiwari Government Hospital, Haldwani to determine myocardial injury by using qualitative cardiac troponin T in critically ill children. In the present study, the mean CK-MB in Troponin T positive cases was 97.32 ± 65.24 and Troponin T negative cases was 58.11 ± 52.05. This was found to be statistically significant (P<0.0001). Conclusion- The present study shows the role of cardiac troponin T in critically ill children to determine myocardial injury. We assessed the correlation between qualitative Troponin T and PELOD score and also the mortality. The correlation of CK-MB and Troponin T was studied and found to be highly significant and related to prognosis, severity, and further management. Further studies with larger sample size are required to validate the findings of the present study

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