ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    DEXMEDETOMIDINE VS. MAGNESIUM SULPHATE IN ADULT PATIENTS UNDERGOING MAXILLECTOMY/MANDIBULECTOMY SURGERY: CHANGES IN INTRAOPERATIVE MAP


    Dr. Rachana N D, Dr. Sumitha C S, Dr Veerbhadra Kalyani, Dr. Prashant Hatti, Dr. Arathi B H, Dr. VB Gowda
    JCDR. 2024: 290-297

    Abstract

    Dexmedetomidine can result in cardiovascular depression, i.e., bradycardia and hypotension due to central presynaptic alpha 2A stimulation, with decreased norepinephrine. The incidence of postoperative bradycardia has been reported to be as high as 40% in healthy surgical patients who received Dexmedetomidine, especially high doses. After obtaining approval from the ethics committee, data was collected from patients coming to Oncology department for elective mandibulectomy/maxillectomy surgeries performed under General Anaesthesia. Patients fulfilling the inclusion criteria were briefed about the procedure and written informed consent taken. Patient demographic details noted. Comparison of MAP between Groups by Unpaired t-test were BL, BI shows no statistical significance difference at p > 0.05 level, whereas in 15 AI, 30 AI, 45AI, 60AI, 90AI, 120 AI, 150AI, 180 AI, 5BE shows highly statistical significance difference at p<0.01 level respectively.

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    Volume 15 Issue 2

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