Abstract

Pre-Eclampsia is a dynamic process. The criterion for diagnosis EO-PE (Early Onset Pre-Eclampsia) and LO-PE (Late Onset Pre-Eclampsia) is almost same, only difference is in the gestational age; because this division is much simplified and has better understanding of the prognostic implications than mild vs severe terminology. It has been done to observe the differences in hematological findings between early & late onset pre eclampsia & to observe the differences in Fetal and Maternal outcome . 60 cases of severe pre-eclampsia were selected from the cases diagnosed & admitted in the labour room of Obstetrics & Gynaecology Dept, VSSIMSAR, Burla. 34 weeks was used as a cut-off to classify patients into Early Onset Pre-eclampsia (EO-PE) and Late Onset Pre-eclampsia (LOPE). Mean GA during admission were between 29-36 weeks . EO-PE group had higher SBP/DBP values, higher Mean Serum Urea, Serum Creatinine, Mean Serum Uric Acid values with increased proteinuria measured by dipstick than LO-PE group. There was more thrombocytopenia in EO-PE. Obstetrical Complications seen more in EO-PE (IUGR, Oligohydramnios, Abruptio, AKI, Eclampsia, HELLP, AEDF, REDF etc). Most of the women underwent termination by LSCS in EO-PE (66.67%) compared to LO-PE (36.67%). (10%) mothers were admitted in ICU in EO-PE, but none were admitted in LO-PE. Mean Baby weight were between 1.47-2.48kgs. 80% neonates in EO-PE were admitted in NICU compared to LO-PE (30%). Early onset pre-eclampsia had more maternal and foetal complications than late onset pre-eclampsia.

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