Journal of Cardiovascular Disease Research
Early Osteoarthritis of Knee an Integrated Approach to Clinical Assessment and Management
Nitin Sanadhya , Jaya Kumari
JCDR. 2023: 1234-1241
Abstract
Background: : Osteoarthritis (OA) is a disease with progressive loss of articular cartilage, which is due to a variety of genetic and environmental risk factors and pathophysiological processes. The main cause of trauma and discomfort in joint mobility leading to disability in osteoarthritis is simultaneous new bone generation and synovial growth. Disruption of articular cartilage, osteophyte generation, subchondral sclerosis, meniscal disintegration, bone marrow lesions, and synovial proliferation are the typical characteristics of osteoarthritis (OA) (1)
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