Abstract

Introduction: Although the use of dexmedetomidine to spinal anaesthesia is becoming more and more common, there isn't much agreement on the recommended dosage. Higher dosages of dexmedetomidine are not advised due to dose-related lengthening of motor blockade duration and an increase in the incidence of side effects, such as bradycardia and hypo tension. Aim: To assess the effectiveness of intrathecal dose of dexmedetomidine (10μg) in conjunction with 0.5% hyperbaric bupivacaine in terms of the anesthesia & quality, specifically enhance the duration of spinal anesthesia, hemodynamic stability, adequate surgical field, the side effects of dexmedetomidine, and the time required to initiate rescue analgesia. Material and Method: 29 patients were randomly selected by American Society of Anaesthesiologist (ASA) Grade I and II orthopaedic patients who were postedbilateral TKR and were between the ages of 45and 70. Ten microgram (μg) of injectable dexmedetomidine (0.5 ml, reconstituted using normal saline) were given to with the total study drug volume remaining constant at 3.5 millilitres for each of the 29 patients. Time to first postoperative rescue analgesia, intraoperative hemodynamic stability and complications.

Description