Abstract

The study emphasizes the effectiveness of percutaneous treatment of liver abscess along with intravenous antibiotics which significantly improved outcome in patients. However In pyogenic and amoebic liver abscess patients having comorbidities like DM or complications like rupture the hospital stay duration, cost of treatment and morbidity was longer. Result Image guided drainage was done in 112 patients (93%). Open surgical drainage (Exploratory laparotomy) was done for 6 cases (5%). Medical treatment (Antibiotic alone) was given to 2 patients (2%). Duration of i/v antibiotics treatment for less than one week was for 45 (37.5%) patients out of 120 patients and those who require more than one week i/v antibiotics treatment were 75 patients (62.5%). From this study we identified the following independent factors affecting the prognosis of patients with liver abscess with respect to duration of treatment, cost of treatment and disability adjusted life years due to morbidity - Jaundice(Hyperbilirubinemia), diabetes mellitus, leukocytosis, Hypoalbunimia, increased SGOT, increased SGPT, uremia, large size of abscess, multiple liver abscesses, hepatomegaly and presence of complication that is ruptured liver abscess. Conclusion In recent scenario, we mainly treat pyogenic and amoebic liver abscess with a combination of parenteral antibiotics and percutaneous drainage with/without pigtail catheter. Patients who are treated with antibiotics only are the ones having an abscess cavity less than 5cm. In pyogenic and amoebic liver abscess patients having jaundice (hyperbilirubinemia) ,diabetes mellitus, increased SGOT, increased SGPT, uremia, large size of abscess, multiple liver abscess, hepatomegaly, and ruptured liver abscess, the hospital stay duration, cost of treatment and morbidity was longer

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