Abstract

Sub-arachnoid block is most commonly used technique in regional anaesthesia to conduct lower limb surgeries [1]. Wide variety of adjuvants have been used intrathecally to prolong post-operative analgesia. The aim of this study is to evaluate and compare the intra-operative block characteristics and duration of postoperative analgesia by using intrathecal dexmedetomidine (5µg) or nalbuphine(1mg) as an adjuvant to hyperbaric bupivacaine (12.5mg) in lower limb orthopedic surgeries. Aims and objectives: This study is used to compare the effects of dexmedetomedine and nalbuphine when given as an adjuvant to hyperbaric bupivacaine in sub-arachnoid block. Material and methods: This study was prospective, randomized, double-blind study. After obtaining ethical committees’ clearance and informed consent, sixty patients of either sex, and ASA physical status I and II scheduled for sub-arachnoid block were included and categorized into two groups(n=30). Result: Addition of dexmedetomedine with hyperbaric bupivacaine intrathecally when compared with nalbuphine result in faster onset of both motor and sensory blockade, with statistically significant longer duration of postoperative analgesia. Conclusion: Both dexmedetomidine and nalbuphine can be used as adjuvant to hyperbaric bupivacaine in spinal anaesthesia but dexmedetomidine along with bupivacaine provide better quality of anaesthesia, and excellent postoperative analgesia when compared with nalbuphine.

Description

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