ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    EFFICACY OF GATA3 EXPRESSION IN BREAST CARCINOMA TISSUE FOLLOWING NEOADJUVANT CHEMOTHERAPY


    R. Priyanka, Shashidhar. H. B, Raviteja C. N, Naveen Kumar Ds
    JCDR. 2024: 358-365

    Abstract

    Background: Breast cancer is a leading cause of cancer-related mortality in women, with a rising incidence globally. Neoadjuvant chemotherapy(NACT) is a standard treatment approach for operable advanced loco-regional breast cancer, aiming to achieve tumor shrinkage, downstaging, and improved surgical outcomes. GATA3 expression has been identified as a significant marker for tumor differentiation, estrogen receptor status, and clinical outcomes in breast cancer. Objectives: To investigate the expression of GATA3 in post-NACT breast carcinoma cases and its utility in confirming histopathological diagnosis of partial and complete response, thereby guiding treatment strategies and predicting patient outcomes.

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    Volume 15 Issue 9

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