Abstract

Background Cancer patients are particularly vulnerable to infections due to their compromised immune systems, which can result from the malignancy itself or from treatments such as chemotherapy, radiotherapy, and bone marrow transplants. These therapies, while targeting cancer cells, also damage normal, rapidly dividing cells, including those in the bone marrow, reducing the production of white blood cells and leaving patients immunocompromised. This heightened vulnerability necessitates the frequent use of antibiotics to prevent and treat infections, but it also increases the risk of developing and spreading AMR. Antimicrobial resistance (AMR) is a significant and growing concern in the field of oncology, posing a serious threat to cancer patients' health outcomes Aim The aim of the study is to study the prevalence of antimicrobial resistance among gram negative organisms isolated from cancer patients seeking care at our hospital. The objective is to study bacterial susceptibility pattern in isolates recovered from cancer patients in our setting to optimise antimicrobial prescribing and optimize antimicrobial stewardship.

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