Abstract

Chronic Kidney Disease (CKD) affects millions worldwide, often leading to alterations in lipid metabolism. This study aims to evaluate the lipid profiles in CKD patients, providing insights into potential biochemical markers and therapeutic targets. Methods: In this cross-sectional study, lipid profiles of 200 patients diagnosed with various stages of CKD were analyzed. Blood samples were collected and tested for total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides. Demographic data and clinical parameters, including age, gender, body mass index, and CKD stage, were recorded. Statistical analysis was conducted to correlate lipid levels with CKD stages. Results: The study revealed significant alterations in lipid profiles correlated with the progression of CKD. Notably, there was an increase in total cholesterol and LDL levels, with a marked decrease in HDL levels in advanced stages of CKD. Triglyceride levels also showed a progressive increase. These changes were more pronounced in patients over 50 years of age and those with a higher BMI. Conclusion: The findings suggest that CKD significantly impacts lipid metabolism, with potential implications for cardiovascular risk in these patients. The study highlights the need for regular monitoring of lipid profiles in CKD patients and suggests potential avenues for targeted therapeutic interventions. Further research is recommended to explore the underlying mechanisms and to evaluate the impact of lipid-lowering therapies in this patient population.

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