Abstract

Background: Chronic alcohol consumption is known to cause liver damage, often reflected in altered liver enzyme levels. This study aims to evaluate the extent and pattern of liver enzyme abnormalities in individuals with a history of chronic alcohol consumption. Methods: In this cross-sectional study, 200 chronic alcohol consumers were selected through convenience sampling from an urban population. Participants were categorized based on their duration and frequency of alcohol consumption. Blood samples were collected and analyzed for liver enzyme levels, including Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), and Gamma Glutamyl Transferase (GGT). Data were analyzed using descriptive and inferential statistics, with a focus on correlations between liver enzyme levels and alcohol consumption patterns. Results: Preliminary findings indicate a significant elevation in AST, ALT, and GGT levels in participants with a longer duration and higher frequency of alcohol consumption. Notably, GGT levels showed the most pronounced increase. The study also found a correlation between elevated enzyme levels and certain demographic factors, including age and gender. Conclusion: This study provides critical insights into the biochemical impact of chronic alcohol consumption on liver health. It underscores the importance of early detection and intervention in individuals with abnormal liver enzyme levels, particularly among high-risk demographics.

Description