Abstract

Background: Patients with cardiovascular disease have an increased risk of developing chronic kidney disease (CKD). However, there is insufficient data on CKD incidence in patients with multiple vascular comorbidities. This study examined predictors of CKD stages 3-5 in patients at risk of cardiovascular disease and used estimated glomerular filtration rate (GFR) to create a nomogram to predict the 5-year risk of incident CKD. Methodology: Out of 100 subjects, 50 were diagnosed with chronic kidney disease and 50 had chronic kidney disease with a cardiovascular complication of either sex and an age range of 18-65 years. Blood urea, Creatinine and CK-MB levels were estimated by EM-200 fully automated machine. IL-6 by ELISA Method. Results: There were 58 males and 42 females among the 100 patients, with an average age of 53.37±24.43 years. The mean levels GFR and IL-6 in CKD 78.39±11.58 and 86.4±21.3 ng/L and in CKD with CVD 98.99±19.36 and 101±10.3 ng/L respectively. Conclusion: Observed value of study parameters highlight the risk prediction with better prognosis for cardiovascular complication in CKD patients.

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