ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Evaluation of liver dysfunction and dyslipidemia in patients with non-alcoholic fatty liver disease


    Nikhil Rajak,Nita Sahi,Anurag Kesarwani
    JCDR. 2023: 2232-2236

    Abstract

    The aim of this study was to determine the lipid profile and liver function tests in patients with nonalcoholic fatty liver disease (NAFLD) and to examine their relationship with NAFLD at various degrees. Material and methods: We included 60 patients of non-alcoholic fatty liver disease in this study, this was a cross section type of study in which lipid profile and liver function tests were performed. Results: Total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) were increased by 45%, 36%, 60% and 43%, respectively, in NAFLD patients.High-density lipoprotein (HDL) levels are low in 33% of NAFLD patients. Similarly, serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were elevated (48% and 37%) respectively, while Serum albumin (31%) decreased in NAFLD patients. Progression in NAFLD was associated with increases in serum TC, TG, VLDL, AST and ALT. At the same time, HDL and albumin decreased. Conclusions: Dyslipidemia patterns of lipid markers and abnormal liver function tests have been observed in NAFLD patients. Dyslipidemia and elevated AST and ALT levels are also associated with increased fatty liver levels in NAFLD patients.

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    Volume & Issue

    Volume 14 Issue 8

    Keywords