Abstract

To evaluate right ventricular dysfunction and its association with multi-dimensional scoring system (BODE Index) in Chronic Obstructive Pulmonary disease (COPD). Material and methodology: It was a prospective observational hospital based research, conducted in TMMC & RC, TMU, Moradabad, U.P. It was a time bound research & all the cases (n=76)confirming inclusion criteria were enrolled in the research during the 18 months of research time after the ethical clearance by Institutional Ethical Committee (IEC).The enrollment screening included a measurement of height, weight and BMI. Each participant's FEV1 was measured using spirometry. Dyspnea, six-minute- walk distance (6MWD) and BODE index was measured. 2D Echocardiography was performed on the a fore-mentioned patients. Results: With decrease in FEV1, 6MWD also decreases with significant correlation (p<0.01). Mean FEV1 in mMRC Class II was 49.50±11.996, in Class III was 35.47±12.279 & in Class IV was 26.67±5.686. Mean FEV1 decreases with increase in dyspnea/mMRC as well as RVSP with statistically significant (p<0.01). RVSP of >40mmHg was found more in class III & IV mMRC as well as only in BODE stage III & IV subjects. Severe PAH was found in BODE stage 3 & 4 only. Conclusion: The results of our research showed that the BODE index can be used to predict RV function, & that rising BODE index parameters are associated with a worsening RVD. Our research shows a strong association between severity of COPD and Right Ventricular dysfunction. Due to the additional therapeutic implications of such problems, echocardiographic screening of COPD patients is both essential & helpful.

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