ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Evaluation of role of gestational age and weight on lipid profile in neonates


    Dr. Jogi Satya Sree Tata, Dr. Sarat Chandra Jalagadugula, Dr. V. Thrishi Sagna, Dr. Jaya Lakshmi Nalavath
    JCDR. 2023: 1265-1271

    Abstract

    To calculate the levels of triglycerides, HDL and LDL cholesterol, as well as total cholesterol, in the cord blood of term and preterm neonates. To calculate the levels of triglycerides, total cholesterol, high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol in the cord blood of neonates. Method: In the proposed study, which was conducted at the Gayatri Vidya Parishad Institute of Health Care and Medical Technology in Visakhapatnam, Andhra Pradesh, India, 100 infants from booked and unbooked expectant mothers underwent a thorough clinical evaluation. Diabetes, hypertension, and heart disease not in the family. The deciding factor, according to New Ballard's scale, will be gestational age. Result: The p value for triglycerides was less than 0.05 when compared to LDL and VLDL. Mean lipid profiles of term (n=62) and preterm (n=38) neonates were compared. LDL and VLDL values in preterm neonates differ (p<0.013 and 0.007). The atherogenic index, triglycerides, VLDL, and total cholesterol all have statistically significant p values. 40 SGA terms as well as 22 AGA terms. Significant proportional disparities in total cholesterol and very low density lipoprotein (p<0.05) show that newborns who are small for gestational age are at risk. Significant p values can be seen for birth weight, head circumference, and HDL. 38 premature neonates had SGA or AGA. AGA and SGA in preterms had different HDL fractions (p<0.05). Conclusion: Preterm SGA neonates had greater TC, TG, LDL, and VLDL readings than preterm AGA neonates did. Compared to term AGA newborns, term SGA neonates had higher readings for TC, TG, and VLDL. AI was significantly higher among people who weighed less than 1.5 kg (P<0.001), which suggested an increased risk of atherosclerosis.

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    Volume & Issue

    Volume 14 Issue 5

    Keywords

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