Abstract

Catharanthus roseus, commonly known as Vinca or Madagascar periwinkle, is a notable plant renowned for its medicinal properties. Originating from Madagascar, this perennial herbaceous evergreen plant has garnered attention due to its rich phytochemical content, which includes antioxidants, antibacterial agents, antifungals, antidiabetics, and anticancer compounds. Of the approximately 130 alkaloids present in Vinca, the most prominent include vinblastine, reserpine, vincristine, raubasin, and ajmalcine. Notably, vinblastine and vincristine were among the first plant-derived anticancer drugs used in clinical practice, extracted from this plant species. This paper reviews recent methods for the preparation of dried Vinca material, extraction of bioactive components, and their isolation. It also provides an overview of the traditional uses and phytochemical profiles of C. roseus. The investigation of Vinca extracts and bioactive compounds underscores their potential as valuable medicinal agents.

Description

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