Abstract

The thyroid is one of the most labile organs in the body and varies with puberty, pregnancy, physiological stress and various pathological states. Diseases of thyroid include functional disorder (hyperthyroidism and hypothyroidism) thyrioditis, Graves’ disease, goitre, and tumours. The present study was a two year prospective study of the FNAC of enlarged thyroid, of 100 patients and their histopathological correlation in 60 cases during two years at teaching institute. Aim: This study profiles the thyroid lesions, compare cytological results with histopathological diagnosis and conclude the accuracy of cytological diagnosis. Materials and methods: The needles, syringes, slides and fixatives are used for FNAC. Leishman stain, rapid haematoxylin stain and pap stain used for histopatholical diagnosis. Results: Out of 100 cases, only 60 cases are correlated and confirmed histopathologically. Out of these 60 cases, 48 cases (80%) were found to be non-neoplastic and 12 cases (20%) were found to be neoplastic lesions. Two were diagnosed as follicular adenoma on cytology, which turned out be Multinodular goiter (MNG) on histopathology. The hypocellularity of smear was due to lack of expertise in technique, which should be taken seriously. Conclusion: There is 93% diagnostic accuracy in cytological and histopathlogical correlation. Thus there is highly significant correlation between cytological and histopatological diagnosis in study group which is highly sensitive and specific. Thus we feel that FNAC of thyroid is a reliable. The OPD procedure was cheap, repeated, and simple and easy it can be safely used in diagnosis of most of thyroid lesion without any serious complication. Though FNAC is useful and diagnostic in most the non-neoplastic and neoplastic lesion. There is a grey zone as far as follicular lesion and follicular neoplasm are concerned. All these equivocal cases should undergo surgical excision

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