Abstract
The essential oils contain Vitex negundo Linn. Used to treat eye disease, toothache, inflammation, vitiligo, splenomegaly, skin ulcers, catarrhal fever, rheumatoid arthritis, gonorrhea and bronchitis. It is also used as a tonic, anthelmintic, emulsifier, menstrual aid, antibacterial, antipyretic, and antihistamine. Preparations from parts of the V. negundo plant cure various diseases such as rheumatic diseases, arthritis, gout, cervicitis, inflammatory diseases of the musculoskeletal system, hemorrhoids (heaps), rheumatic pain, sprains and toothaches. It is used commercially in various Ayurvedic medicines and ointments to wounds, burns, and fungal skin infections. We conclude from in vitro drug diffusion studies that emulgels made of HPMC polymers can help control drug release over long periods, avoid greater fluctuations, and reduce treatment costs. As Emulgels helps improve spreadability, adhesion, viscosity, and extrusion, this new drug delivery is becoming popular, making topical application of hydrophobic drugs a worthy choice for both local and systemic effects.