Abstract

Niosomes were prepared using thin-film hydration and sonication techniques. For the film hydration method, surfactant, cholesterol, stearylamine (65.0:30.0:5.0 mM), and aripiprazole (2 mg) were dissolved in a mixture of chloroform:ethanol (3:1).The solvent was evaporated in vacuo on a field evaporator to form a thin film. Then hydrate the film with 10 ml of phosphate buffer (pH 7.4) using a stirrer. Surfactant, cholesterol, and stearylamine for sonication method (65.0:30.0:5.0 mM) and aripiprazole (2 mg) were placed in a beaker and 10 mL of phosphate buffer (pH 7.4) was added. I let it sit for 5 hours.

Description

.