Journal of Cardiovascular Disease Research
FORMULATION OF ASPIRIN TRANSDERMAL PATCHES USING MATRIX FORM AND ITS IN-VITRO EVALUATION
Mr. Ch. Kishore,Dr. K. Rajitha,Mr. P. Sandeep
JCDR. 2021: 98-108
Abstract
Because of its controlled medication release and increased patient compliance, transdermal drug delivery has drawn significant scientific attention as a novel drug delivery method. The goal of this study was to create an ideal tramadol hydrochloride transdermal patch by employing the right quantity of acceptable polymers. To establish a prolonged release pattern, it was also proposed to manage the drug penetration rate from the device. Supplies and Procedures: Various formulations were created by varying the quantity of excipients used. The optimisation of the formulation with the appropriate qualities was achieved by verifying the physicochemical and biopharmaceutical parameters.
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