Abstract

Granular cell tumour is the soft tissue tumour with neuroectodermal differentiation composed of large cells with eosinophilic, granular cytoplasm. It is very rare, predominantly benign soft tissue tumour involving a wide variety of sites. It shows wide age range, though most common in 30 – 50 year olds but rare in children <5 years or adults >80 years and it shows slight female predominance. Material And Methodology: The present study was undertaken in the department of Pathology, P.D.U. Government Medical College, Rajkot. All the five specimens were fixed in 10% formalin overnight, processed, blocks were made and sectioning was done and stained with Harris haematoxylin and Eosin stain. Result: A series of five cases of granular cell tumours in five patients. All tumours were benign. Females were more affected than males. Common age group affected was in third decade. Most common site affected in the present study was tongue, followed by one case each at supraclavicular region, over phalanx of finger and back. Conclusion: Most granular cell tumours are benign and cured by simple resection. Although granular cell tumours are usually benign and slow growing, it is difficult to distinguish them from malignant lesions. Therefore, it is very important that clinicians and pathologists are aware of their clinical and histopathological features [17].

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