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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Histo pathological changes in the placenta of women with gestational diabetes mellitus


    Dr. Rakesh Kumar Shukla, Dr. Suniti Pandey, Dr. Mirza R. U. Beg, Dr. Archana Mishra
    JCDR. 2023: 30-40

    Abstract

    Gestational diabetes mellitus (GDM) is a common metabolic complication in pregnancy affecting the maternal and foetal wellbeing. Aim: - The aim of this original research article is to investigate the histological changes in placenta of GDM and control women. Method: - This study was done in Rama Medical College & Hospital Kanpur. Placenta sample from 100 cases of GDM and 150 of control women collected and histological changes studied. Result: - In this study, the histological changes revealed that Fibrin was in 78% of GDM. Calcification was seen in 42% of GDM. Infarction was found in 4% of GDM, but in control the histological changes revealed Fibrin in 40%, Calcification was 25.3% and Infarction was 4%. Conclusion: - Gestational diabetes mellitus causes significant histological changes.

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