Journal of Cardiovascular Disease Research
Histo pathological changes in the placenta of women with gestational diabetes mellitus
Dr. Rakesh Kumar Shukla, Dr. Suniti Pandey, Dr. Mirza R. U. Beg, Dr. Archana Mishra
JCDR. 2023: 30-40
Abstract
Gestational diabetes mellitus (GDM) is a common metabolic complication in pregnancy affecting the maternal and foetal wellbeing. Aim: - The aim of this original research article is to investigate the histological changes in placenta of GDM and control women. Method: - This study was done in Rama Medical College & Hospital Kanpur. Placenta sample from 100 cases of GDM and 150 of control women collected and histological changes studied. Result: - In this study, the histological changes revealed that Fibrin was in 78% of GDM. Calcification was seen in 42% of GDM. Infarction was found in 4% of GDM, but in control the histological changes revealed Fibrin in 40%, Calcification was 25.3% and Infarction was 4%. Conclusion: - Gestational diabetes mellitus causes significant histological changes.
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