Abstract

Hyponatremia is a prevalent electrolyte disturbance observed in individuals diagnosed with liver cirrhosis. This condition is closely linked to unfavorable prognostic outcomes and the development of complications such as hepatorenal syndrome and ascites. Methods: The selection of patients was based on a comprehensive evaluation that included clinical examination, biochemical tests, and ultrasound examination of the abdomen. Upon admission to the hospital, all patients underwent a comprehensive examination, which included the assessment of their serum sodium levels. Throughout their hospitalization, the patients were closely monitored and their progress was observed. The assessment of the severity of cirrhosis was conducted based on the Child-Pugh score. The MELD score and MELD-Na score were computed upon admission. Results: A study was conducted on a cohort of 150 patients diagnosed with cirrhosis, revealing that the predominant cause of cirrhosis in this particular investigation was attributed to alcohol consumption. A total of 53% of the participants exhibited hyponatremia, defined as a serum sodium concentration below 136 meq/l. The incidence of complications associated with cirrhosis was found to be higher among patients with hyponatremia. Statistically significant findings indicate that complications such as portal hypertension (57%), hepatic encephalopathy (89.28%), hepatorenal syndrome (42.8%), and hyponatremia are prevalent among patients with cirrhosis. The scores for Child-Pugh, Model for End-Stage Liver Disease (MELD), and MELD-Na are elevated in cases of hyponatremia. Mortality is also observed to be more prevalent in cases of severe hyponatremia.

Description