Abstract

Background: Long-term diabetic complications have a great negative impact on the health-related quality of life of patients with type 2 diabetes mellitus. The study aimed to describe the influence of diabetic complications on HRQoL in patients with type 2 diabetes mellitus. Materials and Methods: A hospital-based cross-sectional study was conducted at a tertiary teaching hospital in India. The study included all patients with type 2 diabetes mellitus above 18 years of age and currently on medication.The study was conducted upon approval from the Institutional Ethics Committee (IEC) and informed consent was taken from all the participants before including them in this study. The European Quality of Life questionnaire (EQ-5D-5L) is used in this study to assess the patient’s health-related quality of life. Results: A total of 200 patients participated in this study. Majority of the study participants, 40.5% were adherent to the medication prescribed by the physician and 59.5% were non-adherentto the medication. Hypertension is found to be the most common diabetic comorbidity and complication and CAD, Stroke, and Nephropathy are less frequent diabetic complications but are found to have a greater impact on HRQoL reduction. The mean EQ VAS score was 78.25 ± 14.60 and the mean EQ Index score was 0.8574 ± 0.1432. Mean EQ VAS scores for males and females were 80.3365 ± 14.0779 and 75.9896 ±14.8965 respectively. The mean EQ Index scores for males and females were 0.8657 ± 0.1458 and 0.8483 ± 0.1405 respectively. The mean scores of the HRQoL (both EQ Index and EQ VAS) were found to decrease with the increase in number of diabetic complications.

Description