Abstract

Background This study investigates the impact of surgically treated endometriosis and endometriomas on ovarian reserve in women experiencing infertility and pelvic pain. Methods The cohort consisted of 58 women with endometriosis or endometriomas, categorized into those with peritoneal disease and those without based on surgical findings. Anti-Mullerian hormone levels were assessed before, after, and six months post-surgery to determine ovarian reserve. Results The study found a significant difference in baseline anti-Mullerian hormone levels between endometrioma and negative laparoscopy groups (1.8 ng/mL vs. 3.2 ng/mL, 95% confidence interval, 2.0-4.4 ng/mL). Conclusion Baseline anti-Mullerian hormone levels were lower in women with endometriomas compared to those without endometriosis, and surgical excision led to a temporary decrease in ovarian reserve. Furthermore, patients with bilateral endometriomas experienced a higher rate of decline compared to those without bilateral involvement. These findings highlight the impact of endometriomas on ovarian reserve and suggest a need for careful consideration in the management of women with endometriosis and fertility concerns. Keywords: Infertility, ovarian reserve, Endometriosis, endometrioma.

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