Abstract

Giardiasis is one of the main causes of diarrhea all over the world and among all age groups, as it infects approximately 285 million people annually. It affects it, including interleukins, including IL-6, IL-11, and IL-15. It is also affected by several hormones such as ghrelin and cholecytokinin. Therefore, the current study aimed to evaluate the concentration of some immunological indicators such as interleukin 6, interleukin 11, and interleukin 15, and to evaluate the concentration of some hormones in children. patients with giardiasis, and an attempt to shed light on the age factor and the region of residence in the change of these indicators when comparing the patient groups and the control group. (300) stool samples were collected from children with diarrhea cases whose age did not exceed ten years from the patients of Samarra General Hospital and some private laboratories from Rural and city population, and the research continued from 1/12/2022 to 1/6/2023. The study included examining samples for male and female children from the countryside and the city. The study included calculating the percentage of people infected with the parasite and the difference between males and females and between rural and city children. The concentration of interleukins (6,11,15) and the hormones ghrelin and cholecysteine were measured. The results showed a higher infection in male children compared to female children, and the infection in village children was high. Compared to the incidence of city children, the results of the statistical analysis showed a significant level (P≤ 0.05), and the results of the statistical analysis showed a significant increase at the level of significance (P ≤ 0.05)in the concentration of interleukin-6 in patient samples compared to healthy subjects, and a significant difference occurred between patients and control In the concentration of interleukin 11, while interleukin 15 did not differ significantly from the control group, while there was a significant difference in the concentration of the hormones ghrelin and cholecystokinin between patients and control

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