Abstract

When used in cases with penetrating eye injuries, succinylcholine can lead to the disastrous complication of vision loss by increasing intraocular pressure and increasing the risk of globe rupture. The goal of this research was to determine if pre-treatment with intravenous dexmedetomidine could mitigate the effects of succinylcholine and intubation on intraocular pressure. Methods: The study was prospective and randomized. After discussing the technique in detail, the study was done on 50 eligible patients with the agreement of an ethical committee and the patients' signed informed consent. Research for this study was carried out at Lifecare Hospital, Baniyas, Abu Dhabi between January 2016 to December 2017. Results: The intraocular pressure of the study group decreased after receiving premedication. After succinylcholine and intubation, IOP rose in all three groups, but in the study groups, it never went beyond pre-treatment levels. The sympathetic response to laryngoscopy and intubation was successfully suppressed at both doses of dexmedetomidine, but hemodynamic stability was better at 0.4 mcg/kg than at 0.6mcg/kg. Conclusion: When it comes to preventing an increase in intraocular pressure (IOP) and dampening the sympathetic response, both dosages of dexmedetomidine i.e. 0.4 mcg/kg and 0.6 mcg/kg are equally effective. Nevertheless, the dose of 0.4 mcg/kg is associated with greater hemodynamic stability. Hence, preventing an increase in intraocular pressure with dexmedetomidine 0.4 mcg/kg may be useful

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