Journal of Cardiovascular Disease Research
Intrathecal chlorprocaine and chloroprocaine with fentanyl for short duration urological, perianal and lower limb surgeries; comparision of sensory parameters
Dr. TJ Pooja Jain, Dr. Vijeta V Rane, Dr. Bandi Harsha Vardhan Reddy, Dr. Vivek K Hosamani
JCDR. 2023: 1287-1290
Abstract
Fentanyl, a lipophilic opioid, as compared to morphine is potent, has rapid onset of action with short duration of action and low CSF concentration, limited rostral spread of narcotic, lesser respiratory depression and early motor recovery. After obtaining the approval from institutional review board and the ethical committee, 60 ASA Grade I and Grade II patients who met inclusion and exclusion criteria who were undergoing short duration urology, lower limb and perianal surgeries were selected. The independent ‘t’ test result shows that there is a significant difference in mean of time for regression to L1(min) between the groups with chloroprocaine with fentanyl group taking longer time to regress to L1(<0.001*). The independent ‘t’ test result shows that there is a significant difference in mean of time for regression to S2(min) between the groups with Chloroprocaine with fentanyl group taking longer time to regress to S2(<0.001*).
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