ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    INTRATHECAL HYPERBARIC BUPIVACAINE 0.5% VERSUS INTRATHECAL HYPERBARIC ROPIVACAINE 0.75% IN LOWER LIMB ORTHOPEDIC SURGERY IN ELDERLY POPULATION – A COMPARATIVE RANDOMIZED SINGLE CENTRE DOUBLE BLINDED STUDY


    SWATI LAHIRI ASIM KUMAR KUNDU DR. MANJUSHREE RAY DR. ARUP CHAKRABORTY GAUTAM LAHIRI
    JCDR. 2023: 3382-3394

    Abstract

    Ropivacaine, has been introduced into clinical practice because of its fewer toxic effects and better hemodynamic stability. 0.75% hyperbaric ropivacaine is nearly identical to bupivacaine in terms of onset of action, quality, and duration of sensory block; produces greater duration of sensory block and has better safety level. This study was aimed to compare clinical efficacy of spinal 0.75% ropivacaine fentanyl with 0.5% bupivacaine fentanyl for lower limb orthopedic surgery in geriatrics population. Methods This study included eighty elderly patients of either sex with American society of Anaesthesiologist (ASA) grade I, II, III scheduled for elective lower limb surgery. The patients were randomized to receive either 15 mg of 0.5% bupivacaine with 25 microgram injection fentanyl (BF group) or 22.5 mg of 0.75% hyperbaric ropivacaine with 25 microgram injection fentanyl (RF group) intrathecally. Intra-operative characteristics of sensory and motor nerve block and adverse effects were noted. Results Baseline characteristics were similar between two groups. The onset of sensory block was more rapid in group BF (6.50 0.430 minutes) in comparison to RF (7.64 0.573 minutes). The mean time to achieve motor block was faster in bupivacaine group then RF group. The mean duration of motor block was longer for BF group (254.0817.574 minutes) than RF group (232.359.434 minutes) and mean duration of sensory block was higher in RF group (286.489.218 minutes) than BF group (273.58 21.330 minutes). Conclusion 0.75% hyperbaric ropivacaine provided near similar block characteristic and more hemodynamic stability and less complication

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    Volume & Issue

    Volume 14 Issue 1

    Keywords