Abstract

Menstrual problems and infertility are best understood and treated with knowledge of gynecological endocrinology. Serum prolactin levels in infertile individuals with menstrual disorder are the focus of this study. Materials and Methods: Patients between the ages of 20 and 40 (the reproductive age range) were split into two groups for a year-long prospective case-control research. Fifty fertile women with normal periods served as the control group, while 150 infertile women with menstrual dysfunctions made up the research group. Serum prolactin levels were checked in addition to other relevant laboratory and radiographic tests to get a full picture of the obstetric history. Results: In this analysis, hyperprolactinemia was shown to occur in 24.6% of participants. Hyperprolactinemia was more common in those with polycystic ovary syndrome (33.3%), oligomenorrhea (27.27%), secondary amenorrhea (30.2%), primary amenorrhea (5.5%), irregular menstruation (9.09%), and 25% of those with regular ovulatory cycles and 40% of those with regular anovulatory cycles. Oligomenorrhea was the most common presenting symptom among hyperprolactinemic patients (48.7%), followed by secondary amenorrhea (35.1%). Patients with secondary amenorrhea had a substantially higher mean blood prolactin level (111.42 ng/mL) compared to those with oligomenorrhea (69.3 ng/mL). Seventy-five point six percent of hyperprolactinemic individuals experienced primary infertility, but only twenty-seven point zero seven percent experienced secondary infertility. (p0.01). Blood prolactin levels were significantly different (p 0.01) between cases with and without galactorrhea, and 66.6% of patients with galactorrhea had hyperprolactinemia. Although 13.5 percent of hyperprolactinemic individuals experienced galactorrhea, this symptom was not consistently present. Conclusion: Regular blood prolactin testing is required for the diagnosis of hyperprolactinemia, a major cause of infertility and menstrual disruption.

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